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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01e6ef7afd8916dd51e431e6ad6240ef0ad272b148d78ff17fb93559f543177a' 
  AND token = '4wNx2bc3Ua8TCxdBVajOfejKFi1mLKnzcq9TgF6Bh+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}