SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ee0da833795d5023386cda90bff854677df50a1d0144eabf8640f3ce46c93c4' 
  AND token = 'M4LQxwcmbMwdvlome4IiWRH9mLiDhAxmSgpt4tES9Sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}