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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fc83ffe9a30a21f79727906e8cef384ce834ca7f0dc53629fa909f13e451858' 
  AND token = 'fHP4rTN0pHVWZccx5RAtkw+AhWrZjcwOFTc4B/5pd+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}