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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6c931b619f9c42a280f1c0b47870a1fe257b1d6b055a3f5504b529e1624c6b6' 
  AND token = 'vV1Mp8OJqY53+COAXvdEaL0zrtZ7N54F+zEjR5NCoYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}