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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c22c6cc92d8e03a4ac01648fb7608708eb60827aac1f25986ccd0b3df5f6d02e' 
  AND token = 'ctDqy0MrJkstMcD6pTe4oAFOWwYbxp3n0evM1TWR54M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}