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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27d688f70e04c2682c0fb3d52e64e6c5e0595356990ba6b313b8b897e0134131' 
  AND token = 'N3225lUDAZg8F6mQzON6qkXXHNu+0xaB6hCj21s8GnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}