SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51cff590d501d156653716a36b55c71fa1225c3f278ddf850683d75bd9152a2b' 
  AND token = '4Cfrje4pi6cE7PIHpRdRMZ5/KbdyZSfjOQZg9TkWeVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}