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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9385e622ef4833d4050354ccc63f295218f0c2f6289d7daf0df3e1946e6d497' 
  AND token = 'MLcKPZyXHJ9bs00tHY9kFQSheclj/rIp/LImFoSPNmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}