SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39fdfe63bcce13728322ceb326c0f6925cffa198d5aa81854a2b09fb6d33b337' 
  AND token = '9rLaj4PX10ZtxquOZn/p6aIsi3YAng2cO/BtJTpM/Ug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}