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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bc9571dd28e6e84bfb15fd0a2c3a809c21469d22a46b8cda1a5366ad15c966d' 
  AND token = 'Z44XFAq5XdAemiISC7GwuRbt1sdeVAK5ChbxcLMQxIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}