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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fde1d47cd333d8320f8c0c4591a21ab0ba382996d7a656dd8ede9d5d7ea1285' 
  AND token = 'GA4ISBJNMESFrj3rTOWqOxR6YJJFjMdRPSgK6lxMhQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}