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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43f1f722c1c8adff273390c323deb0a48da82c2efbdd1e73abc1f76e870bf428' 
  AND token = 'pEz+8uoqRR9jQh5mOZ/u6E963SkDNOauEkuPO+LIiXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}