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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e325fd5c3f92270ff8c8d53206addfae0a5be9cde6fed510c15219db390f1e40' 
  AND token = 'DYnyNFoVRSdw9tCXoUF6KCHibcdmSrVNMqu0FFaacyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}