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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b5e3eb11e37cb0e73604238c592f9d5a86f7a7241a84bfc273e62eeb2515220' 
  AND token = 'DgXRox6/YrGj0S4cf3m1unUHjT6K9EyUACREXbT/vl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}