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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e61026f43e3e1b07811d0ab1b1dc16b6030272bbbc524ae91a6021efebddd334' 
  AND token = 'ScKd5mO30yf+n5r2H8fKIqPYQEDk8wWeElbgY8cNCXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}