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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46c23f21252857d90eb7189dbd12e277e8366653cc80cc594c92b139c1581c41' 
  AND token = 'Pi5pLUVhPhbs5YzWa4efnvceosodmpHa4R6gYR/nv2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}