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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1c59d23b3830e1e6ddefbe5bb94e688616f2a39d5c34d9fdac9b56c3542f911' 
  AND token = '7IIG56ih0NAG9Oa2mcVSnpIrFk21Bw1v9svqDB+BIEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}