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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39ee6fbfa52b9809eb7aa1ea11b392a016f182358a6aeafbac8b9095d18f307c' 
  AND token = 'lmXtbXB+RCSZvDHMyiZLiFmLHudP3MSWInyvViqNABI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}