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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d9c05bc16977983625e0939c56e6bc69195313e5bb5c1f92144736fd6b453d1' 
  AND token = 'zioJohe6HS/2QRv20YcInDDBYj8vdrfY86v0FHY4OVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}