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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80c91750013587d58ff4f569a357d7ff601e1bc9631bc8d3e88f4a58364c344d' 
  AND token = 'tjG/d0Z5WRx1AMrsnDUKjzqtkNTOx0A14PGTp12VaQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}