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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81eb3c6c46a86037397f57f1843f90e17ce7daa831846832c5ad60c3eef0491e' 
  AND token = 'lGWDQLe+aKDmPp52KHk4Hc2b33Ht+ORPOOrGti4lvvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}