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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e10d22b0741046a53d8cc917bf787b9e9444d602376b9347093d23e772436021' 
  AND token = 'FErUFSt7UvebAZMSMl1GYuqj8pTf+uODVidGdCEUgbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}