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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d1aa9fd631266e9fe3d71030310d76a14a16df7840497012b180f128292c4b2' 
  AND token = 'xGCniPs7dD2p0kUu7phc9uF7e81V12Hy0kOdNyW6O1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}