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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af91f72f5c9a75b8828e07c2b165bc27acb3396b21832ab1fcf81d16f31273f3' 
  AND token = 'AhPvCNUOQqhMJHXcAdBC22Bofnut/Ex0Lf/0RS13Uyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}