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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44d94268777e29fb2fa0bb393b779c2cc3afb13f4c10d69cfac7feb289f50de4' 
  AND token = '5Z7VcnsMF9vRrHamBQfneERRW4cubx5cEbwU8BbFZYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}