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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b9557514138ceebeb56ce0f73e89f20443406f6a7b0badb213d0a93e1e83f0b' 
  AND token = 'w+sRInzNoHaR97DI43B2PM2RTf3aF1Tcz2kC0NwRBfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}