SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '454d1a0e830315d6adf3d7ab76fc500544e00bd481516950b0d6208656f0a6ae' 
  AND token = 'aGirPbKUYmLJa3FG64I/P9EpXUjFmB5cfdvUIpDru20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}