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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e623becd20417dd803160180273b64cb1a5c01549161da618e57ce2023bfb923' 
  AND token = 'E63aBBQ1WB+9P7ULocSAst7rZoxNWRC0XUsw8qHea9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}