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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb1975474a54d01700bf75fc84cc25c3f1421f725a7e59cae92b95d47163e0a1' 
  AND token = 'eEHSErP+lkl9WGMah4JMM/0jXGk2RusVeR2CLUmcxd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}