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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c139267a5a6b9325dc30b242e220b4c0237cf3a49f58b53cf4495530ba9ce68' 
  AND token = 'XaQJo7YHBJWNnUTnhLqmV6X2EFL5x0XN1hAuBRmF1f8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}