SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64099b1f0fdf953aaa36221d0d86546cc3fa9066d2b2dd41a42dab2ddae49978' 
  AND token = 'jWPY5VvocEDAk8nKjx2BuWv0/I4yOWyO0WcnQIoQnAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}