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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fc2df6eef065b5390a24e5db036981673c32c60e4626bbb500a075955f90da4' 
  AND token = 'MguS9BXQKTQvmu8Kzu1RI00+4biVuWcg748XFYT9CuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}