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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '666e4f312faee31b4f610dd21eaf2bebcf06532a1ae7d2e78d5e9c18187c8850' 
  AND token = 'k3vwPeatOYHonM5bt1GUjMDNsjGSBQrozBwY23fr1B4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}