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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '218778d3ab9cd7f94ec95d65756deee52ac3f22f43d245c66678bfdf67d21431' 
  AND token = 'kx0oanoe/ORryBZZgFz32EQdVYFWhI9RRtYjDQtitXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}