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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7460faca6ac05d0481b3c0230658e27523a2a0f3378c8af0739b77df9b3c4456' 
  AND token = 'VD9lmS1l6PJm02lV7Wn9rMT9fXRZ/hvH+HUtWY5LkSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}