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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '953327eeba00e880a575d34078d096997a5f35347552ca01abc223ccbc9ad87c' 
  AND token = 'QOeT2tIYx85wWDoqM4bSl66/Ev3IuXxCzafH04HttrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}