SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48f95930b29fccd5d5a782a2cfd0fcd0f9924e68d88864a8515470ab79f5a698' 
  AND token = 'E5H/SqPPuLj/RYFk9i8ITTZj/jPZF5lY7Lf0koGZEJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}