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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3266ca3e39609e178e158dc61f8b275df585bc94f3c4026545628d359a70feff' 
  AND token = 'mNznItxz/dsWcdNOLX+CCpbyFqgWHvW6NjS2hRi42fE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}