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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27d4f30f3e6a0c6eae8191afbe72c1d63b72715f535d12c1d533cc72e8be5077' 
  AND token = 'ylMW3p+28+X/ueCRIfnyadJbW0XR5+Cb43B/gSezcpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}