SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cffe166b278736c97fda44d9310e29e443b60302a9fe327ba95ad8c4bc0a2443' 
  AND token = '5QI5ZUtBOHbkjgNQLt6z9fK7wZ9zzYb+Neg7u4nVDNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}