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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6c388cd7fbbedba7f7e51b219435d000d1b67c33bc6328c76401610f17b80af' 
  AND token = '3wx5hmqwtHU2qO2gq5swZHQ1AFG94EXlj+yB6jTH460=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}