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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22ddbefccd7bdb0971a0ee537254c3d3f6bfb45d0dcc854fc87f77f43256ca80' 
  AND token = '1bl5lA913ABl7bi7rmMFLbTJLBV0lpJ4VkcMxh0MQmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}