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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e72f0c18a88edd134c3339125fc96692aa504646c9efeaf552e4e9bfde31f2f' 
  AND token = '9mUTWhjzre954PXvdVACP+ldXf9+4OvqC2xlYTFVdpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}