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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f5c45e9373ed0049424b01d4b6c4f8308a76fbe8ba3b790cc10791846f6e357' 
  AND token = 'Ize7d1WcNLjtrmf45Nx274Ze3vPYFuwQaqEiIN+nsb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}