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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46ded3d372991d19b385b3a5131d1d602079777e11751cbfcfa591e266d3d3d1' 
  AND token = 'EiPytulAKNN+nfImk776+L9jC+379AhpNLiIJx+c6XU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}