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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1424dfc162709d6d49ac432d9a88c02aa4c517feab5aa7b1bfb80d1f20c3e7e0' 
  AND token = 'DtG97hDLtMalTduXWY5fPmSrJThE7jPSkLIdi4VLi8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}