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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b0b1b10a1462462d369b16f03550e3023c0f0b0984fcdc701e5e41bc4a7208d' 
  AND token = '57QnNbu7UM3VkGL2q/G1nSlfEO1HrTABJ1FIfzGPxJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}