SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e16f4649e2ed046328358e99249cb571d32a90ef460e970b02856ce20bcf2988' 
  AND token = '5c10wdL0HRyd0MbtT/Qjd/aqzNMmj4dDwvEmqnzDcSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}