SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7495ffc045204ca2e5362f4ab2c416c27734fc4a80a0083f3a4b505a7d14af3c' 
  AND token = '1faf0TDKs9YMKvz/LEYz2N2ef0uQrw4RdSOAk+rp5ps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}