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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2dc64ce6cabd40e51acf7a0a681bd74932cd5f65b75d82fceae9b7614007862' 
  AND token = '+QTua1jy6zb9k+V8KK40hv8kgnIcHJ4Lc4vIE0sOoHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}